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Metformin generic brands. Patents are not the only patent related risks. FDA reports an average of $1.5 billion in annual lost revenue for pharmaceutical companies because of delayed patent filings, or delays, by the drug companies; some estimates are as high $5bn dollars per year. (See sidebar on page 24). The United States, with less than a tenth the population of China, is home to nearly 8 million patents (see sidebar on page 9). In the US, there are an estimated 800,000 pending patent applications. Patents are the primary reason why generic manufacturers cannot do basic drugs such as aspirin to meet patients' needs. In the UK alone, FDA's drugs department alone has had more than 1,000 cases of unapproved generic versions a patented drug, and is aware Drugstore brow gel of about 150 other cases (FDA, 1997). In Canada, metformin buy online the FDA is investigating about 12 cases of unapproved generic versions drugs, involving about 7,000 patent applications (Paraquet, 1994). The pharmaceutical industry has shown itself willing to invest large sums obtain the most patents, and not enough to make substantial generic competition. As a result, only tiny minority of generics is able to enter the market. Predictably, the market for generic medicines is much smaller than for patented metformin online australia drugs. According to the 1995 Survey of International Pharmaceutical Markets, there were about 1.5 per cent of the world's population using less than 100 generic medicines. In contrast, pharmaceutical companies spent an estimated $3.8 billion on patent licensing in 1997 the US alone, and an estimated $10.9 billion in Canada (FDA, 1997). Patent licensing accounts for more than 50 per cent of the US pharmaceutical industry's total sales revenue (U.S. Department of Commerce, 1998). The failure of generics has created a vicious circle in Canadian health care financing, which the public is forced to pay a higher percentage of their bill, as more and drugs become unavailable. The proportion of total costs reimbursed by Canada's health insurance companies is estimated to be about 60 per cent of total expenditures, though this is far lower than most other countries, and some people complain that Canadians do not metformin online canada get enough bang for their buck (Nauroth 1995, p. 9). And yet the same countries have negotiated drug prices that are considerably lower, not higher as in the US. Although the cost of generic drugs is much lower than for branded drugs, they must compete with expensive brand-name medicines for the limited supply of patients.
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